Epson requires the user to download drivers for their printers from Apple. Often, Apple Software Update will report the drivers are not available at this time and send the user to Epson. Finding current drivers is difficult and registering the printer to the newly installed drivers requires one simple step…not covered in any instructions.

First, the user must be have an admin account. Download the drivers from http://support.apple.com/kb/DL1398 and open the install package. Follow the instructions to install the drivers.

Second, shut down the system and plug the printer in via USB.

Third, restart and log into an admin account.

Forth, (the simple, overlooked step) DISCONNECT FROM INTERNET

Fifth, If your system offers a dialog to add your printer, follow the instructions. If not, then open System Preferences/Printers & Scanners. Click on the + to add your printer.

OSX, unconnected from the Internet, should find the drivers you installed in the first step.
…

Source: Mac OSX Hints